Design and synthesis of a very potent peptide to enhance cell adhesion

 

We designed a peptide containing both moieties to enhance specific and nonspecific cell adhesion. Following a successful peptide synthesis and decoration of material surface, we found via cell experiments that the agent might be the most potent oligopeptide so far. (Yuxiao Lai, Cao Xie, Zheng Zhang, Weiyue Lu, Jiandong Ding*, Design and synthesis of a potent peptide containing both specific and non-specific cell adhesion motifs, Biomaterials, 31, 4809-4817 (2010).)