Seven papers of Ding group are selected as “Highly cited papers (latest 10 years)” by ESI, and 6 of them are regarded as “Core Papers” of “Research Front”

Essential Science Indicators (ESI) is for statistics of scientific performance and trends. According to ESI available from ISI-Web of Knowledge on June 14, 2013, 7 corresponding-author papers of Professor Jiandong DING have been listed in global “Highly Cited Papers (last 10 years)”. They are

l  In vitro degradation of three dimensional porous poly(D,L-lactide-co-glycolide) scaffolds for tissue engineering

Linbo Wu, Jiandong Ding*, Biomaterials, 25(27), 5821-5830 (2004) (The research article is for tissue engineering scaffolds. This is the first paper Professor Ding published in the field of biomedical materials.)

l  Injectable hydrogels as unique biomedical materials

        Lin Yu, Jiandong Ding*, Chem. Soc. Rev., 37, 1473-1481 (2008) (The review concerns injectable hydrogels especially for drug delivery systems. This is the first review Professor Ding wrote for an international journal.)

l  Impact of order and disorder in RGD nanopatterns on cell adhesion

Jinghuan Huang, Stefan V. Gräter, Francesca Corbellini, Sabine Rinck-Jahnke, Eva Bock, Ralf Kemkemer, Horst Kessler, Jiandong Ding*, and Joachim P. Spatz*, Nano Lett., 9(3), 1111-1116 (2009) (This letter is for cell-biomaterial interaction on nanoscale, achieved from a Sino-German international cooperation.)

l  The regulation of stem cell differentiation by cell-cell contact on micropatterned material surfaces

Jiang Tang, Rong Peng, Jiandong Ding*, Biomaterials, 31, 2470–2476 (2010) (This research article studies cell-biomaterial interactions based upon micropatterned surfaces. Especially, unique material techniques were developed to reveal the basic science of stem cells.)

l  Biodegradable and thermoreversible PCLA–PEG–PCLA hydrogel as a barrier for prevention of post-operative adhesion

 Zheng Zhang, Jian Ni, Liang Chen, Lin Yu, Jianwei Xu*, and Jiandong Ding*, Biomaterials, 32, 4725-4736 (2011) (This research article reports the first thermogel as postoperative anti-adhesion. The animal experiments exhibited a better efficacy than the clinical products of films. The work was made in cooperation with a Surgeon group.)

l  Enhancement of the fraction of the active form of an antitumor drug topotecan via an injectable hydrogel

Guangtao Chang, Tianyuan Ci, Lin Yu, Jiandong Ding*, J. Controlled Release, 156, 21-27 (2011) (This research article reports the first encapsulation of the antitumor drugs in the camptothecin (CPT) family into thermogel. The CPT drugs exist as a form of either lactone or carboxylate, but only the former with a closed E-ring has the antitumor efficacy and the lactone fraction at physiological pH is quite low. The minor fraction became a major one after the drug was encapsulated into the physical hydrogel induced by body temperature, and the main reason was not local pH but some unknown interaction between drugs and materials. Very good drug efficacy was observed in mice experiments.)

l  Control of cell nucleus shapes via micropillar patterns

 Zhen Pan, Ce Yan, Rong Peng, Yingchun Zhao, Yao He, and Jiandong Ding*, Biomaterials, 33, 1730-1735 (2012) (The research article reports the serious self deformation of cell nuclei on appropriate microarrays, while the examined mesenchymal stem cells were still alive and able to experience osteogenic differentiation. The shapes of cell nuclei were further controlled by designing microarray patterns.)

The latter 6 papers were also selected by ESI into “research front” as “Core Paper” (according to the record of 2013-06-14).

l  The Chem. Soc. Rev. (2008) first-authored by Dr. Lin YU, Biomaterials (2011) first-authored by Mr. Zheng ZHANG, a Ph.D student, and J. Controlled Release (2011) first-authored by Mr. Guangtao CHANG, a Ph.D student, are three of five Core Papers in research front of “Injectable Hydrogels; In-Situ Gelling Stimuli-Sensitive Block Copolymer Hydrogels; Thermoreversible PCLA-PEG-PCLA Hydrogel; Antitumor Drug Topotecan; Biodegradable Thermogels”.

l  The Nano Lett. (2009) first-authored by Ms. Jinghuan HUANG, Biomaterials (2010 first-authored by Mr. Jian TANG, a Ph.D student, and Biomaterials (2012) first-authored by Mr. Zhen PAN, a Ph.D student, are three of four Core Papers in research front of “Cell Adhesion; Cell Nucleus Shapes; Stem Cell Differentiation; Cell Spreading; Focal Adhesion Dynamics”.