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News and notes

●	Ding’s group revealed the mechanism of ring-opening polymerization of cyclic esters catalyzed by isooctanoate using density functional theory (DFT)

●	Ding’s group conducted both theoretical and experimental studies on reorientation of cells on an elastic polymer under uniaxial cyclic stretching and put forward the concept of critical stretching rate

●	Ding’s group developed an intelligent transdermal formulation of spontaneous asymmetry

●	Cell migration is regulated by RGD nanospacing and enhanced under moderate cell adhesion on biomaterials

●	Ding’s group revealed that material surface topography regulated nuclear shape, chromosomal repositioning and gene expressions of cells

●	A simplified yet enhanced and versatile microfluidic platform for cyclic cell stretching on an elastic polymer

●	Ding’s group developed 3D printing of biomacromolecular porous scaffolds using “nascent hydrogel” of modified gelatin for osteochondral regeneration

●	Ding’s group revealed the mechanism of the molecular weight distribution effects on thermogelation of triblock copolymer PLGA-PEG-PLGA
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●	Ding’s group elucidated the structure and mechanism of the PLGA-PEG-PLGA thermogel

●	Ding’s group reveals a dynamic cue to regulate stem cells —— degradation rate of materials

●	Ding’s group revealed the structure of PEG/PLGA thermogel and the underlying mechanism of the physical gelation

●	Non-monotonic self-deformation of cell nuclei on polymeric topological surfaces revealed by JD Ding’s group

●	Four students and postdoctors from Ding’s group won Excellent Posters in Biomaterials Congress

●	Jinadong Ding’s group attended 2017 China conference on biological materials

●	Effects of functional groups of materials on non-specific adhesion and chondrogenic differentiation of stem cells revealed by JD Ding’s group

●	Professor DING was awarded as one of Leading Talent Scientists by Chinese Central government

●	Professor DING was elected as Fellow (FBSE) by International Union of Societies for Biomaterials Science and Technology due to his “development of cell responsive biomaterials for tissue engineering, regenerative medicine and drug delivery”

●	Degree thesis supervised by Prof. Ding was evaluated as Excellent Ph.D thesis once again by Shanghai Education Committee and Shanghai Degree Committee

●	Nuclear shape ¾ a new cell geometry cue to regulate stem cell differentiation

●	First International Conference of Molecular Engineering of Polymers (MEP-1 or MEP-2016) held at Fudan University in October 2016

●	An “abnormal” effect of matrix stiffness on stem cell differentiation

●	Ministry of Science and Technology grants a State Key Project of Research and Development “Biomaterial Surfaces/Interfaces and Corresponding Surface Modifications” undertaken by 26 scholars from 10 universities and hospitals and led by Prof. Ding

●	A single subcutaneous injection of the mixture of a peptide drug and a polymeric thermogel treats type 2 diabetes for as long as one week ¾ as article first-authored by Mr. Yipei CHEN, a master student was published in Scientific Reports 2016

●	“Injectable Thermogel” won “Innovation Award” in 2015 China International Industry Fair

●	“Injectable Thermogel” won “Excellent Product Award” in 2015 China Hi-Tech Fair

●	Professor Ding taught a tutorial course “Biodegradation of Polymers” invited by MRS Fall Meeting of 2015 held in Boston

●	Professor Ding gave an invited lecture about in vivo medical applications of thermogels in MRS meeting (2015, Boston)

●	Professor Ding visited Harvard University and MIT, and gave academic lectures twice in Harvard at the end of 2015

●	Ph.D student Mr. Kai YE won Poster Award in National Congress of Macromolecules 2015

●	Associate Professor YU, Ph.D student Ye and master student Li in our group won Young Scientist Awards in three sessions in National Congress of Biomaterials 2015

●	Professor Ding gave a plenary lecture in National Congress of Biomaterials 2015 along with American professors

●	Effects of cell-cell contact on chondrogenic differentiation of stem cells revealed via unique micropatterning techniques ¾ an article first-authored by a Ph.D student Mr Bin CAO was published in Biomaterials 2015

●	A novel micro/nanopatterning technique for studies of stem cell differentiation ¾ a paper first-authored by a Ph.D student Ms. Xuan WANG was published in Nano Letters 2015

●	Nanoscale spatial arrangement of RGD peptides influences dedifferentiation of chondrocytes ¾ a paper first-authored by a master student Mr. Shiyu LI was published in Nano Letters 2015

●	Professor Ding was awarded as Best Associate Editor by Science Bulletin

●	Professor Jiandong DING visited USA in summer of 2015 and gave academic presentations in MIT twice

●	Professor Jiandong DING and Associate Professor Lin YU won First-Rate Prize for Research in Natural Sciences awarded by State Ministry of Education

●	Postdoctor positons open for candidates all over the world University

●	Professor Jiandong DING was invited as a member of Editorial Advisory Board by Macromolecules, a journal of American Chemical Society (ACS) at the beginning of 2015

●	Ph. D thesis supervised by Prof. Ding was awarded as Excellent Thesis by Shanghai Education Committee and Shanghai Degree Committee

●	Tumor regression by encapsulating a moderately soluble drug into a polymeric thermogel ¾ an article first-authored by a Ph.D student Ms. Tianyuan CI was published in Scientific Reports 2015

●	Ding’s group discovered the effect of molecular weight distribution of block copolymers on micellization and gelation

●	Regulation of chondrocyte dedifferentiation revealed via micropatterning techniques

●	Prof. Ding gave a plenary lecture (45 min) in IUPAC New Materials Congress 2014

●	Surface chirality influences stem cell differentiation

●	Cell-material interactions revealed by surface patterning ¾ 10 years of efforts led to 30 printed pages of a review article in Advanced Materials 2013

●	Prof. Ding gave a plenary lecture (40 min) in National Congress of Macromolecules 2013

●	Seven papers of DING group are selected as “Highly cited papers (latest 10 years)” by ESI, and 6 of them are regarded as “Core Papers” of “Research Front”

●	Professor Ding gave a plenary lecture in NanoBio International Conference in USA and seminars in Harvard, Pennsylvania and Columbia Universities.

●	Dr. Guoqiang XU, a previous student under supervision of Professor Ding, was offered a distinguished professorship in Soochow University, China, and awarded as a State Young Qian-ren Researcher.

●	RGD nanospacing is a regulator of stem cell differentiation ¾ an article first-authored by a Ph.D student Ms Xuan WANG was published in Biomaterials 2013

●	Simply addition of PEG homopolymer enhances the efficacy of camptothecin drugs ¾ an article first-authored by a Ph.D student Ms Tianyuan CI was published in Journal of Controlled Release 2013

●	Porous scaffolds of a polymer-bioceramics composite repair bonds via in vivo tissue engineering¾ an article from co-operation was published in Int. J. Nanomed.

●	Bilayered PLGA scaffolds repair osteochondral defects in a rabbit model ¾ an article from co-operation was published in J. Biomed. Mater. Res. Part A 2013

●	Professor DING was awarded as “Shanghai Leading Talent” by Bureau of Personnel, Shanghai

●	Long-acting antidiabetic carrier ¾ an article from co-operation was published in Biomaterials 2013

●	Cellular aspect ratios regulate stem cell differentiation in growth media ¾ an article first-authored by a Ph.D student Mr Xiang YAO was published in Biomaterials 2013

●	Summary of 10-year efforts in PLGA porous scaffolds for tissue engineering and pertinent progress in DING group and other groups ¾ a review was published in Interface Focus, a new Royal Society journal

●	Professor DING was awarded as “Shanghai Leading Scientist” by Committee of Science and Technology of Shanghai

●	16 group members attended the 9^th World Congress of Biomaterials, and Professor Ding chaired the symposium 10.3 “Directing cell-material interactions with patterned surfaces” in the Congress

●	Mr. Zhen Pan, a Ph.D student under supervision of Professor Ding owned Poster Award in the 9^th World Congress of Biomaterials

●	Effects of cell size, cell density and cell-cell contact on differentiation of stem cells as revealed via a micropatterning technique ¾¾ an article first-authored by a Ph.D student Miss Rong PENG was accepted by Biomaterials

●	Cell nuclei can be deformed significantly and controlled by designing micropillar arrays¾¾ an article first-authored by a Ph.D student Mr. Zhen PAN was published in Biomaterials

●	The SCI citation of Professor Ding by others is over 1,000, and the annual citation has rapidly been increased in the recent years

●	Semi-quantitative studies of cell shape as a cue to tune differentiation of stem cells under induction media ¾¾ an article first-authored by a Ph.D student Miss Rong PENG was published in Biomaterials

●	A polymeric hydrogel was found to significantly alter the equilibrium of the transformation between active and inactive forms of an anti-tumor drug ¾¾ an article first-authored by a Ph.D student Mr. Guangtao CHANG was published in Journal of Controlled Release

●	Dr. Jian LIU, a previous group member under supervision of Professor Ding was offered a distinguished professorship in Soochow University, China, and awarded as a State Young Qian-ren Researcher in 2011.

●	Dr. Qi ZHANG, a previous group member under supervision of Professor Ding was offered an assistant professorship in University of North Carolina in 2011.

●	Four corresponding-author papers of Professor DING were recorded by Essential Science Indicator (ESI) as “Highly Cited Papers”, and three of them published in 2008, 2009 and 2010 were regarded to represent “Research Front”

●	Till 2011, the group has more than 100 papers published in SCI journals

●	Critical areas of cell adhesion on micropatterned surfaces¾¾a paper first-authored by a Ph. D student Sakuen was published in Biomaterials (2011)

●	An injectable hydrogel for post-operative anti-adhesion ¾¾ a paper first-authored by a Ph.D student Fisher was published in Biomaterials (2011)

●	Sequence of copolymer controls gellability of the corresponding block copolymers in water ¾¾a paper first-authored by Lin was published in Biomacromolecules (2011)

●	The Key Program (973) about Biomaterials headed by Professor Ding as Leading Scientist passed successfully over the mid-evaluation by Chinese Ministry of Science and Technology.

●	Two corresponding-author papers of Professor DING rank well according to ESI record

●	Differentiation of stem cells is regulated by cell communication as revealed by material’s surface-patterning technique ¾¾ a paper first-authored by a Ph.D student Mr. Jian TANG was published in Biomaterials (2010)

●	Design and synthesis of a very potent peptide to promote cell adhesion ¾¾ a paper first-authored by a Ph.D student Ms. Yuxiao LAI was published in Biomaterials (2010)

●	Effects of immobilizing sites of RGD peptides in amphiphilic block copolymers on efficacy of cell adhesion -- a manuscript first-authored by a Ph.D student Mr. Zheng ZHANG was accepted by Biomaterials in 2010

●	Professor DING was invited to contribute a Highlight about nanostructured biomimetic surface by a RSC journal Soft Matter

●	A biodegradable nanoparticle targeting to extratumor pH ¾¾ a paper first-authored by a Ph.D student Mr. Guangtao CHANG was accepted by Macromolecular Bioscience (2010)

●	Biodegradability and biocompatibility of thermoreversible hydrogels of block copolymers ¾¾ a paper first-authored by Dr. Lin YU was accepted by Biomacromolecules (2010)

●	Roles of non-native hydrogen bonds in helix-coil transition of polypeptide ¾¾ a paper first-authored by a former Ph.D student Mr. Yantao CHEN was published in Proteins (2010)

●	Fabrication of hybrid micro-nano patterns ¾¾ a paper first-authored by a Ph.D student Mr. Peng LIU was published in Langmuir (2010)

●	Self assembly of amphiphilic synthetic polymers with biological membranes significantly adjusts functions of membrane proteins ¾¾ a full paper first-authored by a Ph.D student Mr. Dewang MA was accepted by Soft Matter (2010)

●	Professor DING was awarded Nominee Prize of Feng Xinde in June 2010

●	pK_a is not a constant for amphiphilic polymeric inomers ¾¾ a paper first-authored by a Ph.D student Mr. Guangtao CHANG was published in Polymer (2009)

●	Finding of the longest lifetime of M intermediate of bacteriorhodopsin under high water content ¾¾ a paper first-authored by a Ph.D student Mr. Dewang MA was published in Soft Matter (2009)

●	Professor Ding was appointed as Leading Scientist of a Key Program (973) about Nano-biomaterials from Chinese Ministry of Science and Technology (2009.01-2013.12).

●	Professor Ding was invited to review “polymeric medical materials” by Chemical Society Reviews

●	The Key Grant of Chinese Ministry of Education “Fundamental researches of cell/biomaterial interactions based upon patterned surfaces” headed by Professor Ding was evaluated to be finished with excellent achievements on July 28, 2009. The evaluation committee organized by Ministry of Education comments this work as “a significantly advanced and interdisciplinary research”.

●	Order parameter of nano patterns can tune cell adhesion --a paper first-authored by a Ph. D student, Ms Jinghuan HUANG was published in Nano Letters (2009).

●	An efficient photoelectric approach to determine pKa of excited retinal proteins -- an article first-authored by a pH. D student Mr. Jia WU was published in Journal of Physical Chemistry B (2009).

●	“Solution” plus “precipitate” leads to sol-gel transition -- an article first-authored by Dr. Lin YU was published in Biomacromolecules (2009).

●	Up to July 2009, an article published in Biomaterials in Dec, 2004 has been cited 70 times by others according to SCI. This paper was first-authored by a postdoctor Mr. Linbo WU.

●	The annual SCI citation of our group by others reaches over 100 in 2008.

●	Discontinuous induction of bone marrow stem cells could result in a better osteoplastic differentiation -- an article first-authored by a Ph. D student Ms. Zhen WANG was published in Biotechnology Progress (2008).

●	An approach to generate regular and stable micropatterns with cell adhesion contrast on hydrogels -- a communication first-authored by a Ph.D student Mr. Jianguo SUN was published in Biomacromolecules (2008).

●	Self-avoiding chains under different dimensions in a constrained geometry exhibit different dynamic scaling laws -- an article first-authored by a Ph.D student Mr. Ting CUI was published in Physical Review E (2008).

●	Molecular dynamics simulation of folding of a beita-hairpin -- an article first-authored by a Ph.D student Ms. Zhonglin LUO was published in Journal of Chemical Physics (2008).

●	Chemically-crosslinked micelles could serve as building blocks of physical hydrogels -- a paper first-authored by a Ph. D student, Mr. Zigang YANG was published in Macromolecular Rapid Communications (2008)

●	Why does an addition of hydrophilic PEG enhance physical gelation due to hydrophobic association? -- an article first-authored by a Ph. D student Mr. Huan ZHANG was published in Macromolecules (2008).

●	The thesis of Mr. Lin YU supervised by Professor Ding was warded as excellent Ph.D thesis of Fudan University in 2008. The pertinent work was also awarded as one of three first-class prizes of Chinese Pharmacy Congress in 2008.

●	Professor Ding was elected as a committee member of Biomaterials Sub-society, Biomedical Engineering Society of China.

●	Up to July, 2007, our group has contributed 100 papers in refereed journals. 68 papers have been published in the journals recorded by Science Citation Index (SCI), in which 60 papers are first-authored or corresponding-authored by Professor Ding.

●	Up to July, 2007, 10 invention patents claimed by our group have been approved.

●	A paper with Stefan, a Ph. D student as the first author has been published in *Nano Letters* (2007). Stefan was co-supervised by Professor Spatz and Professor Ding.

●	Postdoctor positions open for those with the background of Polymer, Biomaterials, Cell Biology, Organic Synthesis, Biomedical Engineering, Surgery, Pharmaceutics, Molecular Biology or any other majoring related to our interdisciplinary research.

●	The pathway of protein folding is dependent upon temperature ¾¾ a paper first-authored by a Ph. D student, Ms. Zhonglin LUO will be published in *Biophysical Journal* (2007)

●	A classic theory of helix-coil transition revisited ¾¾ a paper first-authored by a Ph. D student, Mr. Yantao CHEN will be published in *Proteins* (2007).

●	Adjusting spontaneous physical gelling of block copolymers in water via molecular designing¾¾ a paper first-authored by a Ph. D student, Mr. Lin YU has been published in Journal of Polymer Science, Polymer Chemistry Edition (2007).

●	Rheology of complex fluids used in preparation of biomaterials ¾¾ a paper first-authored by a Ph. D student, Mr. Dianying JING will be published in *Macromolecular Bioscience* (2007).

●	A novel technique of sustained release carriers via combination of intelligent injectable hydrogels and drug PEGylation ¾¾ a paper (with both in vitro and in vivo experiments) first-authored by a Ph. D student, Mr. Lin YU will be published in *International Journal of Pharmaceutics* (2007).

●	At the beginning of 2007, four Ph. D students (Ms. Wenqi LU, Mr. Ming MING, Mr. Yantao CHEN, and Mr. Lin YU) graduated together.

●	In the year of 2006, our group has a series of first-institution & corresponding-author papers published in SCI journals. 8 of the papers were published in the Journals with impact factor > 3.0.

●	Materials Society of China launched the Sub-society of Biomedical Materials in 2006. Professor DING was selected as a committee member.

●	Professor DING was selected as a committee member of Biophysics Society of China.

●	Professor DING renewed the member of Biomaterials Committee, Shanghai Society of Biomedical Engineering in 2006.

●	Molecular design and synthesis of a novel injectable hydrogel ¾¾ a paper first-authored by a Ph. D student, Mr. Lin YU was published in Angwante Chemie (2006).

●	A novel processing technique of tissue engineering scaffold ¾¾ a paper first-authored by a postdoctor, Dr. Linbo WU was published in Biomaterials (2006).

●	A novel membrane protein was found in a Tibet strain by the researchers of Fudan University ¾¾ its light driven proton pumping mechanism was revealed, and a paper first-authored by a Ph. D student, Mr. Ming MING was published in Biophysical Journal (2006)

●	The first dynamic Monte Carlo simulation of polymerization and network formation of self assembled amphiphilic macromonomers ¾¾ a paper first-authored by a Ph. D student, Ms. Wenqi LU was published in Macromolecules (2006).

●	Scaling of intramacromolecular cyclization revealed by a computer simulation¾¾ a paper first-authored by a Ph. D student, Mr. Ting CUI was published in Macromolecules (2006).

●	Chain length distribution in lipid bilayer and process of vesicle fusion ¾¾ a paper first-authored by a Ph. D student, Mr. Shichen JI was published in Langmuir (2006).

●	Surfactants can alter the time order of proton release and uptake in a membrane protein ¾¾this finding was published in FEBS Letter (2006) first-authored by a Ph. D student, Mr. Ming MING.

●	A coarse grained model of helix-coil transition of polypeptide ¾¾ a paper first-authored by a Ph. D student, Mr. Yantao CHEN was published in Journal of Chemical Physics (2006).

●	A novel thermosensitive and biodegradable microgel and associated post-fabrication encapsulation strategy of protein drugs ¾¾ a paper first-authored by a postdoctor, Dr. Yang ZHANG was published in Journal of Controlled Release (2005).

●	A novel technique of fabrication of porous scaffolds for tissue repair ¾¾ a paper first-authored by a postdoctor, Dr. Linbo WU was published in Tissue Engineering (2005)